The substance specified in the Annex, belonging to the additive category ‘nutritional additives’ and to the functional group ‘amino acids, their salts and analogues’, is authorised as an additive in animal nutrition subject to the conditions laid down in that Annex.
This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union .
ANNEXSupplementary provisions
ANNEX
Identification number of the additive
Name of the holder of authorisation
Additive
Composition, chemical formula, description, analytical method.
Species or category of animal
Maximum age
Minimum content
Maximum content
Other provisions
End of period of authorisation
mg/kg of complete feed with a moisture content of 12 %
Category of nutritional additives. Functional group: amino acids, their salts and analogues
3c305
—
L-methionine
Additive composition
L-methionine with a purity of at least 98,5 %
Characterisation of the active substance
L-methionine ((2S)-2-amino-4-(methylthio) butanoic acid) produced by fermentation with Escherichia coli (KCCM 11252P and KCCM 11340P)
Chemical formula: C 5 H 11 NO 2 S
CAS number: 63-68-3
Analytical method
( 1 )
For the identification of L-methionine in the feed additive: infrared absorption and optical rotation — FCC monographs methods.
For the quantification of methionine in the feed additive and premixtures containing more than 10 % of methionine: ion exchange chromatography coupled with post-column derivatisation and photometric or fluorescence detection (HPLC-VIS/FD) — ISO/DIS 17180.
For the determination of methionine in premixtures containing less than 10 % of methionine, compound feed, feed materials and water: ion exchange chromatography coupled with post-column derivatisation and photometric detection (HPLC/VIS) — Commission Regulation (EC) No 152/2009 ( 2 ) (Annex III, F).
All species
—
1.
L-methionine can be also used via water for drinking.
2.
Declarations to be made on the labelling of the additive and premixtures:
‘If the additive is administered via water for drinking, excess protein should be avoided.’
3.
Where voluntary declaration of the additive is made on the labelling of feed materials and compound feed, the following shall be included:
—
name and identification number of the additive,
—
added amount of the additive.
26 August 2024
( 1 ) Details of the analytical methods are available at the following address of the Reference Laboratory: https://ec.europa.eu/jrc/en/eurl/feed-additives/evaluation-reports
( 2 )
OJ L 54, 26.2.2009, p. 1 .