Commission Delegated Regulation (EU) 2021/849 of 11 March 2021 amending, for the purposes of its adaptation to technical and scientific progress, Part 3 of Annex VI to Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)

Amendments to Regulation (EC) No 1272/2008

Article 1

Table 3 of Part 3 of Annex VI to Regulation (EC) No 1272/2008 is amended as set out in the Annex to this Regulation.

Entry into force and application

Article 2

This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union . It shall apply from 17 December 2022. By way of derogation from the second paragraph of this Article, substances and mixtures may be classified, labelled and packaged in accordance with this Regulation from its date of entry into force.

ANNEXSupplementary provisions

ANNEX In Annex VI to Regulation (EC) No 1272/2008, Table 3 of Part 3 is amended as follows: (1) the following entries are inserted: Index No Chemical Name EC No CAS No Classification Labelling Specific Conc. Limits, M- factors and ATE Notes Hazard Class and Category Code(s) Hazard statement Code(s) Pictogram, Signal Word Code(s) Hazard statement Code(s) Suppl. Hazard statement Code(s) ‘601-093-00-6 1,4-dimethylnaphthalene 209-335-9 571-58-4 Acute Tox. 4 Asp. Tox. 1 Eye Irrit. 2 Aquatic Acute 1 Aquatic Chronic 3 H302 H304 H319 H400 H412 GHS07 GHS08 GHS09 Dgr H302 H304 H319 H410   oral: ATE = 1 300 mg/kg bw M = 1’   ‘601-094-00-1 1-isopropyl-4-methylbenzene; p -cymene 202-796-7 99-87-6 Flam. Liq. 3 Acute Tox. 3 Asp. Tox. 1 Aquatic Chronic 2 H226 H331 H304 H411 GHS02 GHS06 GHS08 GHS09 Dgr H226 H331 H304 H411   inhalation: ATE = 3 mg/l (vapours)’   ‘601-095-00-7 p -mentha-1,3-diene; 1-isopropyl-4-methylcyclohexa-1,3-diene; alpha-terpinene 202-795-1 99-86-5 Flam. Liq. 3 Acute Tox. 4 Skin Sens. 1 Asp. Tox. 1 Aquatic Chronic 2 H226 H302 H317 H304 H411 GHS02 GHS07 GHS08 GHS09 Dgr H226 H302 H317 H304 H411   oral: ATE = 1 680 mg/kg bw’   ‘602-110-00-X tetrafluoroethylene 204-126-9 116-14-3 Carc. 1B H350 GHS08 Dgr H350’       ‘604-095-00-5 6,6'-di- tert -butyl-2,2'-methylenedi- p -cresol; [DBMC] 204-327-1 119-47-1 Repr. 1B H360F GHS08 Dgr H360F’       ‘606-152-00-X (5-chloro-2-methoxy-4-methyl-3-pyridyl)(4,5,6-trimethoxy- o -tolyl)methanone; pyriofenone - 688046-61-9 Carc. 2 Aquatic Chronic 1 H351 H410 GHS08 GHS09 Wng H351 H410   M = 1’   ‘607-747-00-7 2,2-dibromo-2-cyanoacetamide; [DBNPA] 233-539-7 10222-01-2 Acute Tox. 2 Acute Tox. 3 STOT RE 1 Skin Irrit. 2 Eye Dam. 1 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H330 H301 H372 (respiratory tract) (inhalation) H315 H318 H317 H400 H410 GHS06 GHS08 GHS05 GHS09 Dgr H330 H301 H372 (respiratory tract) (inhalation) H315 H318 H317 H410   inhalation: ATE = 0,24 mg/l (dusts or mists) oral: ATE = 118 mg/kg bw M = 1 M = 1’   ‘607-748-00-2 [ S -( Z , E )]-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid; S -abscisic acid 244-319-5 21293-29-8 Aquatic Acute 1 Aquatic Chronic 1 H400 H410 GHS09 Wng H410   M = 1 M = 1’   ‘607-749-00-8 methyl salicylate 204-317-7 119-36-8 Repr. 2 Acute Tox. 4 Skin Sens. 1B Aquatic Chronic 3 H361d H302 H317 H412 GHS07 GHS08 Wng H361d H302 H317 H412   oral: ATE = 890 mg/kg bw’   ‘607-750-00-3 citric acid 201-069-1 77-92-9 Eye Irrit. 2 STOT SE 3 H319 H335 GHS07 Wng H319 H335’       ‘607-751-00-9 ethametsulfuron-methyl (ISO); methyl 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate - 97780-06-8 Eye Irrit. 2 Aquatic Acute 1 Aquatic Chronic 1 H319 H400 H410 GHS07 GHS09 Wng H319 H410   M = 1 000 M = 100’   ‘607-752-00-4 trinexapac-ethyl (ISO); ethyl 4-[cyclopropyl(hydroxy)methylene]-3,5-dioxocyclohexanecarboxylate - 95266-40-3 STOT RE 2 Skin Sens. 1B Aquatic Chronic 1 H373 (gastrointestinal tract) H317 H410 GHS08 GHS07 GHS09 Wng H373 (gastrointestinal tract) H317 H410   M = 1’   ‘607-753-00-X (3a S ,5 S ,6 R ,7a R ,7b S ,9a S ,10 R ,12a S ,12b S )-10-[(2 S ,3 R ,4 R ,5 R )-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3 H -benzo[ c ]indeno[5,4- e ]oxepin-3-one; 24-epibrassinolide - 78821-43-9 Aquatic Chronic 4 H413   H413’       ‘607-754-00-5 benzyl salicylate 204-262-9 118-58-1 Skin Sens. 1B H317 GHS07 Wng H317’       ‘607-755-00-0 ( RS )-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)- o -toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate; tolpyralate - 1101132-67-5 Carc. 2 Repr. 2 STOT RE 2 Aquatic Acute 1 Aquatic Chronic 1 H351 H361fd H373 (eye) H400 H410 GHS08 GHS09 Wng H351 H361fd H373 (eye) H410   M = 10 M = 100’   ‘613-337-00-9 prothioconazole (ISO); 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazole-3-thione - 178928-70-6 Aquatic Acute 1 Aquatic Chronic 1 H400 H410 GHS09 Wng H410   M = 10 M = 1’   ‘613-338-00-4 azamethiphos (ISO); S -[(6-chloro-2-oxooxazolo[4,5- b ]pyridin-3(2 H )-yl)methyl] O , O -dimethyl thiophosphate 252-626-0 35575-96-3 Carc. 2 Acute Tox. 3 Acute Tox. 4 STOT SE 1 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H351 H331 H302 H370 (nervous system) H317 H400 H410 GHS06 GHS08 GHS09 Dgr H351 H331 H302 H370 (nervous system) H317 H410   inhalation: ATE = 0,5 mg/l (dusts or mists) oral: ATE = 500 mg/kg bw M = 1 000 M = 1 000 ’   ‘613-339-00-X 3-methylpyrazole 215-925-7 1453-58-3 Repr. 1B Acute Tox. 4 STOT RE 2 Skin Corr. 1 Eye Dam. 1 H360D H302 H373 (lung) H314 H318 GHS08 GHS07 GHS05 Dgr H360D H302 H373 (lung) H314   oral: ATE = 500 mg/kg bw’   ‘613-340-00-5 clomazone (ISO); 2-(2-chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one - 81777-89-1 Acute Tox. 4 Acute Tox. 4 Aquatic Acute 1 Aquatic Chronic 1 H332 H302 H400 H410 GHS07 GHS09 Wng H332 H302 H410   inhalation: ATE = 4,85 mg/l (dusts or mists) oral: ATE = 768 mg/kg bw M = 1 M = 1’   ‘614-030-00-2 emamectin benzoate (ISO); (4" R )-4"-deoxy-4"-(methylamino) avermectin B1 benzoate - 155569-91-8 Acute Tox. 3 Acute Tox. 3 Acute Tox. 3 STOT SE 1 STOT RE 1 Eye Dam. 1 Aquatic Acute 1 Aquatic Chronic 1 H331 H311 H301 H370 (nervous system) H372 (nervous system) H318 H400 H410 GHS06 GHS05 GHS08 GHS09 Dgr H331 H311 H301 H370 (nervous system) H372 (nervous system) H318 H410   inhalation: ATE = 0,663 mg/l (dusts or mists) dermal: ATE = 300 mg/kg bw oral: ATE = 60 mg/kg bw STOT RE 1; H372: C ≥ 5 %; STOT RE 2; H373: 0,5 % ≤ C < 5 % M = 10 000 M = 10 000 ’   ‘616-234-00-7 N -methoxy- N -[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide; pydiflumetofen - 1228284-64-7 Carc. 2 Repr. 2 Aquatic Acute 1 Aquatic Chronic 1 H351 H361f H400 H410 GHS08 GHS09 Wng H351 H361f H410   M = 1 M = 1’   ‘616-235-00-2 N -{2-[[1,1'-bi(cyclopropyl)]-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1 H -pyrazole-4-carboxamide; sedaxane - 874967-67-6 Carc. 2 Aquatic Acute 1 Aquatic Chronic 2 H351 H400 H411 GHS08 GHS09 Wng H351 H410   M = 1’   (2) the entries corresponding to index numbers 005-007-00-2; 005-008-00-8; 005-011-00-4; 005-011-01-1; 005-011-02-9; 006-069-00-3; 006-076-00-1; 015-113-00-0; 028-007-00-4; 029-002-00-X; 029-015-00-0; 029-016-00-6; 029-017-00-1; 029-018-00-7; 029-019-01-X; 029-020-00-8; 029-021-00-3; 029-022-00-9; 029-023-00-4; 601-029-00-7; 601-096-00-2; 603-024-00-5; 603-066-00-4; 603-098-00-9; 606-004-00-4; 607-421-00-4; 607-424-00-0; 607-434-00-5; 608-058-00-4; 612-067-00-9; 612-252-00-4; 613-048-00-8; 613-102-00-0; 613-111-00-X; 613-166-00-X; 613-208-00-7; 613-267-00-9; 613-282-00-0; 616-032-00-9; 616-106-00-0 and 616-113-00-9 are replaced by the following entries respectively: Index No Chemical Name EC No CAS No Classification Labelling Specific Conc. Limits, M- factors and ATE Notes Hazard Class and Category Code(s) Hazard statement Code(s) Pictogram, Signal Word Code(s) Hazard statement Code(s) Suppl. Hazard statement Code(s) ‘005-007-00-2 boric acid [1] boric acid [2] 233-139-2 [1] 234-343-4 [2] 10043-35-3 [1] 11113-50-1 [2] Repr. 1B H360FD GHS08 Dgr H360FD’       ‘005-008-00-8 diboron trioxide 215-125-8 1303-86-2 Repr. 1B H360FD GHS08 Dgr H360FD’       ‘005-011-00-4 tetraboron disodium heptaoxide, hydrate; [1] disodium tetraborate, anhydrous; [2] orthoboric acid, sodium salt [3] disodium tetraborate decahydrate [4] disodium tetraborate pentahydrate [5] 235-541-3 [1] 215-540-4 [2] 237-560-2 [3] 215-540-4 [4] 215-540-4 [5] 12267-73-1 [1] 1330-43-4 [2] 13840-56-7 [3] 1303-96-4 [4] 12179-04-3 [5] Repr. 1B H360FD GHS08 Dgr H360FD’                                                   ‘006-069-00-3 thiophanate-methyl (ISO); dimethyl (1,2-phenylenedicarbamothioyl)biscarbamate; dimethyl 4,4′-( o -phenylene)bis(3-thioallophanate) 245-740-7 23564-05-8 Carc. 2 Muta. 2 Acute Tox. 4 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H351 H341 H332 H317 H400 H410 GHS08 GHS07 GHS09 Wng H351 H341 H332 H317 H410   inhalation: ATE = 1,7 mg/l (dusts and mists) M = 10 M = 10’   ‘006-076-00-1 mancozeb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric) complex with zinc salt - 8018-01-7 Carc. 2 Repr. 1B STOT RE 2 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H351 H360D H373 (thyroid, nervous system) H317 H400 H410 GHS08 GHS07 GHS09 Dgr H351 H360D H373 (thyroid, nervous system) H317 H410   M = 10 M = 10’   ‘015-113-00-0 tolclofos-methyl (ISO); O -(2,6-dichloro- p -tolyl) O , O -dimethyl thiophosphate 260-515-3 57018-04-9 Skin Sens. 1B Aquatic Acute 1 Aquatic Chronic 1 H317 H400 H410 GHS07 GHS09 Wng H317 H410   M = 1 M = 1’   ‘028-007-00-4 trinickel disulfide; nickel subsulfide; [1] heazlewoodite [2] 234-829-6 [1] - [2] 12035-72-2 [1] 12035-71-1 [2] Carc. 1A Muta. 2 Acute Tox. 3 STOT RE 1 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H350i H341 H331 H372** H317 H400 H410 GHS08 GHS06 GHS09 Dgr H350i H341 H331 H372** H317 H410   inhalation: ATE = 0,92 mg/l (dusts or mists)’   ‘029-002-00-X dicopper oxide; copper (I) oxide 215-270-7 1317-39-1 Acute Tox. 4 Acute Tox. 4 Eye Dam. 1 Aquatic Acute 1 Aquatic Chronic 1 H332 H302 H318 H400 H410 GHS07 GHS05 GHS09 Dgr H332 H302 H318 H410   inhalation: ATE = 3,34 mg/l (dusts or mists) oral: ATE = 500 mg/kg bw M = 100 M = 10’   ‘029-015-00-0 copper thiocyanate 214-183-1 1111-67-7 Aquatic Acute 1 Aquatic Chronic 1 H400 H410 GHS09 Wng H410 EUH032 M = 10 M = 10’   ‘029-016-00-6 copper(II) oxide 215-269-1 1317-38-0 Aquatic Acute 1 Aquatic Chronic 1 H400 H410 GHS09 Wng H410   M = 100 M = 10’   ‘029-017-00-1 dicopper chloride trihydroxide 215-572-9 1332-65-6 Acute Tox. 4 Acute Tox. 3 Aquatic Acute 1 Aquatic Chronic 1 H332 H301 H400 H410 GHS06 GHS09 Dgr H332 H301 H410   inhalation: ATE = 2,83 mg/l (dusts or mists) oral: ATE = 299 mg/kg bw M = 10 M = 10’   ‘029-018-00-7 tetracopper hexahydroxide sulphate; [1] tetracopper hexahydroxide sulphate hydrate [2] 215-582-3 [1] 215-582-3 [2] 1333-22-8 [1] 12527-76-3 [2] Acute Tox. 4 Aquatic Acute 1 Aquatic Chronic 1 H302 H400 H410 GHS07 GHS09 Wng H302 H410   oral: ATE = 500 mg/kg bw M = 10 M = 10’   ‘029-019-01-X copper flakes (coated with aliphatic acid) - - Acute Tox. 3 Acute Tox. 4 Eye Irrit. 2 Aquatic Acute 1 Aquatic Chronic 1 H331 H302 H319 H400 H410 GHS06 GHS09 Dgr H331 H302 H319 H410   inhalation: ATE = 0,733 mg/l (dusts or mists) oral: ATE = 500 mg/kg bw M = 10 M = 10’   ‘029-020-00-8 copper(II) carbonate—copper(II) hydroxide (1:1) 235-113-6 12069-69-1 Acute Tox. 4 Acute Tox. 4 Eye Irrit. 2 Aquatic Acute 1 Aquatic Chronic 1 H332 H302 H319 H400 H410 GHS07 GHS09 Wng H332 H302 H319 H410   inhalation: ATE = 1,2 mg/l (dusts or mists) oral: ATE = 500 mg/kg bw M = 10 M = 10’   ‘029-021-00-3 copper dihydroxide; copper(II) hydroxide 243-815-9 20427-59-2 Acute Tox. 2 Acute Tox. 4 Eye Dam. 1 Aquatic Acute 1 Aquatic Chronic 1 H330 H302 H318 H400 H410 GHS06 GHS05 GHS09 Dgr H330 H302 H318 H410   inhalation: ATE = 0,47 mg/l (dusts or mists) oral: ATE = 500 mg/kg bw M = 10 M = 10’   ‘029-022-00-9 bordeaux mixture; reaction products of copper sulphate with calcium dihydroxide - 8011-63-0 Acute Tox. 4 Eye Dam. 1 Aquatic Acute 1 Aquatic Chronic 1 H332 H318 H400 H410 GHS07 GHS05 GHS09 Dgr H332 H318 H410   inhalation: ATE = 1,97 mg/l (dusts or mists) M = 10 M = 1’   ‘029-023-00-4 copper sulphate pentahydrate 231-847-6 7758-99-8 Acute Tox. 4 Eye Dam. 1 Aquatic Acute 1 Aquatic Chronic 1 H302 H318 H400 H410 GHS07 GHS05 GHS09 Dgr H302 H318 H410   oral: ATE = 481 mg/kg bw M = 10 M = 1’   ‘601-029-00-7 dipentene; limonene [1] ( S )- p -mentha-1,8-diene; l-limonene [2] trans -1-methyl-4-(1-methylvinyl)cyclohexene; [3] (±)-1-methyl-4-(1-methylvinyl)cyclohexene [4] 205-341-0 [1] 227-815-6 [2] 229-977-3 [3] 231-732-0 [4] 138-86-3 [1] 5989-54-8 [2] 6876-12-6 [3] 7705-14-8 [4] Flam. Liq. 3 Skin Irrit. 2 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H226 H315 H317 H400 H410 GHS02 GHS07 GHS09 Wng H226 H315 H317 H410     C’ ‘601-096-00-2 ( R )- p -mentha-1,8-diene; d-limonene 227-813-5 5989-27-5 Flam. Liq. 3 Skin Irrit. 2 Skin Sens. 1B Asp. Tox. 1 Aquatic Acute 1 Aquatic Chronic 3 H226 H315 H317 H304 H400 H412 GHS02 GHS07 GHS08 GHS09 Dgr H226 H315 H317 H304 H410   M = 1’   ‘603-024-00-5 1,4-dioxane 204-661-8 123-91-1 Flam. Liq. 2 Carc. 1B STOT SE 3 Eye Irrit. 2 H225 H350 H335 H319 GHS02 GHS08 GHS07 Dgr H225 H350 H335 H319 EUH019 EUH066   D’ ‘603-066-00-4 7-oxa-3-oxiranylbicyclo[4.1.0]heptane; 1,2-epoxy-4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide 203-437-7 106-87-6 Carc. 1B Muta. 2 Repr. 1B Acute Tox. 3 Acute Tox. 4 H350 H341 H360F H331 H302 GHS08 GHS06 Dgr H350 H341 H360F H331 H302   inhalation: ATE = 0,5 mg/l (dusts or mists) oral: ATE = 1 847 mg/kg bw’   ‘603-098-00-9 2-phenoxyethanol 204-589-7 122-99-6 Acute Tox. 4 STOT SE 3 Eye Dam. 1 H302 H335 H318 GHS05 GHS07 Dgr H302 H335 H318   oral: ATE = 1 394 mg/kg bw’   ‘606-004-00-4 4-methylpentan-2-one; isobutyl methyl ketone 203-550-1 108-10-1 Flam. Liq. 2 Carc. 2 Acute Tox. 4 STOT SE 3 Eye Irrit. 2 H225 H351 H332 H336 H319 GHS02 GHS07 GHS08 Dgr H225 H351 H332 H336 H319 EUH066 inhalation: ATE = 11 mg/l (vapours)’   ‘607-421-00-4 cypermethrin (ISO); α-cyano-3-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; cypermethrin cis/trans +/- 40/60 257-842-9 52315-07-8 Acute Tox. 4 Acute Tox. 4 STOT SE 3 STOT RE 2 Aquatic Acute 1 Aquatic Chronic 1 H332 H302 H335 H373 (nervous system) H400 H410 GHS07 GHS08 GHS09 Wng H332 H302 H335 H373 (nervous system) H410   oral; ATE = 500 mg/kg bw inhalation; ATE = 3,3 mg/l (dusts or mists) M = 100000 M = 100000’   ‘607-424-00-0 trifloxystrobin (ISO); methyl ( E )-methoxyimino-{( E )-α-[1-(α,α,α-trifluoro- m -tolyl)ethylideneaminooxy]- o -tolyl}acetate - 141517-21-7 Lact. Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H362 H317 H400 H410 GHS07 GHS09 Wng H362 H317 H410   M = 100 M = 10’   ‘607-434-00-5 mecoprop-P (ISO) [1] and its salts; ( R )-2-(4-chloro-2-methylphenoxy)propionic acid [1] and its salts 240-539-0 [1] 16484-77-8 [1] Acute Tox. 4 Eye Dam. 1 Aquatic Acute 1 Aquatic Chronic 1 H302 H318 H400 H410 GHS07 GHS05 GHS09 Dgr H302 H318 H410   oral: ATE = 431 mg/kg bw M = 10 M = 10’   ‘608-058-00-4 esfenvalerate (ISO); (S)-α-cyano-3-phenoxybenzyl-( S )-2-(4-chlorophenyl)-3-methylbutyrate - 66230-04-4 Acute Tox. 3 Acute Tox. 3 STOT SE 1 STOT RE 2 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H331 H301 H370 (nervous system) H373 H317 H400 H410 GHS06 GHS08 GHS09 Dgr H331 H301 H370 (nervous system) H373 H317 H410   oral; ATE = 88,5 mg/kg bw inhalation; ATE = 0,53 mg/l (dusts or mists) M = 10 000 M = 10 000 ’   ‘612-067-00-9 3-aminomethyl-3,5,5-trimethylcyclohexylamine 220-666-8 2855-13-2 Acute Tox. 4 Skin Corr. 1B Eye Dam. 1 Skin Sens. 1A H302 H314 H318 H317 GHS05 GHS07 Dgr H302 H314 H317   oral: ATE = 1 030 mg/kg bw Skin Sens. 1A; H317: C ≥ 0,001 %’   ‘612-252-00-4 imidacloprid (ISO); ( E )-1-(6-chloro-3-pyridylmethyl)- N -nitroimidazolidin-2-ylideneamine; (2 E )-1-[(6-chloropyridin-3-yl) methyl]- N -nitroimidazolidin-2-imine 428-040-8 138261-41-3 Acute Tox. 3 Aquatic Acute 1 Aquatic Chronic 1 H301 H400 H410 GHS06 GHS09 Dgr H301 H410   oral: ATE = 131 mg/kg bw M = 100 M = 1 000 ’   ‘613-048-00-8 carbendazim (ISO); methyl benzimidazol-2-ylcarbamate 234-232-0 10605-21-7 Muta. 1B Repr. 1B Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 H340 H360FD H317 H400 H410 GHS07 GHS08 GHS09 Dgr H340 H360FD H317 H410   M = 10 M = 10’   ‘613-102-00-0 dimethomorph (ISO); ( E , Z )-4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl)morpholine 404-200-2 110488-70-5 Repr. 1B Aquatic Chronic 2 H360F H411 GHS08 GHS09 Dgr H360F H411’       ‘613-111-00-X 1,2,4-triazole 206-022-9 288-88-0 Repr. 1B Acute Tox. 4 Eye Irrit. 2 H360FD H302 H319 GHS08 GHS07 Dgr H360FD H302 H319   oral: ATE = 1 320 mg/kg bw’   ‘613-166-00-X flumioxazin (ISO); N -(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2 H -1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboximide - 103361-09-7 Repr. 2 Aquatic Acute 1 Aquatic Chronic 1 H361d H400 H410 GHS08 GHS09 Wng H361d H410   M = 1 000 M = 1 000 ’   ‘613-208-00-7 imazamox (ISO); ( RS )-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid - 114311-32-9 Repr. 2 Aquatic Acute 1 Aquatic Chronic 1 H361d H400 H410 GHS08 GHS09 Wng H361d H410   M = 10 M = 10’   ‘613-267-00-9 thiamethoxam (ISO); 3-(2-chloro-thiazol-5-ylmethyl)-5-methyl[1,3,5]oxadiazinan-4-ylidene- N -nitroamine 428-650-4 153719-23-4 Repr. 2 Acute Tox. 4 Aquatic Acute 1 Aquatic Chronic 1 H361fd H302 H400 H410 GHS07 GHS08 GHS09 Wng H361fd H302 H410   oral: ATE = 780 mg/kg bw M = 10 M = 10’   ‘613-282-00-0 triticonazole (ISO); ( RS )-( E )-5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1 H -1,2,4-triazol-1-methyl)cyclopentanol - 138182-18-0 Repr. 2 STOT RE 2 Aquatic Acute 1 Aquatic Chronic 1 H361f H373 H400 H410 GHS08 GHS09 Wng H361f H373 H410   M = 1 M = 1’   ‘616-032-00-9 diflufenican (ISO); N -(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]-3-pyridinecarboxamide; 2′,4′-difluoro-2-(α,α,α-trifluoro- m -tolyloxy) nicotinanilide - 83164-33-4 Aquatic Acute 1 Aquatic Chronic 1 H400 H410 GHS09 Wng H410   M = 10 000 M = 1 000 ’   ‘616-106-00-0 phenmedipham (ISO); methyl 3-(3-methylcarbaniloyloxy)carbanilate 237-199-0 13684-63-4 Aquatic Acute 1 Aquatic Chronic 1 H400 H410 GHS09 Wng H410   M = 10 M = 10’   ‘616-113-00-9 desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate 237-198-5 13684-56-5 Repr. 2 Aquatic Acute 1 Aquatic Chronic 1 H361d H400 H410 GHS08 GHS09 Wng H361d H410   M = 10 M = 10’   (3) the entry corresponding to index number 015-192-00-1 is deleted.