Commission Implementing Regulation (EU) 2021/2093 of 29 November 2021 concerning the authorisation of disodium 5'-guanylate as a feed additive for all animal species (Text with EEA relevance)
Commission Implementing Regulation (EU) 2021/2093 of 29 November 2021 concerning the authorisation of disodium 5'-guanylate as a feed additive for all animal species (Text with EEA relevance)
Data as of 2026-07-04 · Compiled from an official source version. Later amendments or repeals may not be reflected; the official text prevails. · Read the official text ↗
The substance specified in the Annex, belonging to the additive category ‘sensory additives’ and to the functional group ‘flavouring compounds’, is authorised as an additive in animal nutrition, subject to the conditions laid down in that Annex.
ANNEX
Identification number of the additive
Name of the holder of authorisation
Additive
Composition, chemical formula, description, analytical method
Species or category of animal
Maximum age
Minimum content
Maximum content
Other provisions
End of period of authorisation
mg active substance/kg of complete feed with a moisture content of 12 %
Category: Sensory additives
Functional group: Flavouring compounds
2b627i
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Disodium 5'-guanylate
Additive composition
Disodium 5'-guanylate (GMP).
Powder form
Characterisation of the active substance
Disodium 5'-guanylate (hydrated form) produced with Corynebacterium stationis KCCM 10530 and Escherichia coli K-12 KFCC 11067.
Produced by fermentation
Purity: min.: 97 %
Chemical formula:
C 10 H 12 N 5 Na 2 O 8 P
CAS number: 5550-12-9
Einecs number: 226-914-1
Analytical method
( 1 )
For the identification of disodium 5'-guanylate (GMP) in the feed additive:
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FAO JECFA monograph ‘disodium 5'-guanylate’
For the determination of disodium 5'-guanylate (GMP) in the feed additive, flavouring premixtures and water:
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High performance liquid chromatography coupled to UV detection (HPLC-UV)
All animal species
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1.
The additive shall be incorporated into the feed in the form of a premixture.
2.
In the directions for use of the additive and premixtures, the storage conditions and stability to heat treatment shall be indicated.
3.
On the label of the additive the following shall be indicated:
‘Recommended maximum content of the active substance when used alone or in combination with other ribonucleotides up to the same level per kg of complete feedingstuff with a moisture content of 12 %: 50 mg’.
4.
The functional group, the identification number, the name and the added amount of the active substance shall be indicated on the label of the premixture where the use level on the label of the premixture would result in exceeding the level of active substance in complete feedingstuff referred to in point 3.
20 December 2031
( 1 ) Details of the analytical methods are available at the following address of the Reference Laboratory: https://ec.europa.eu/jrc/en/eurl/feed-additives/evaluation-reports