Article 1
The work programme for the gradual review of the safeners and synergists already used in plant protection products is hereby adopted. Annex I to Regulation (EU) 2024/1487 is amended in accordance with the Annex to this Regulation.
Commission Regulation (EU) 2025/2274 of 12 November 2025 amending Regulation (EU) 2024/1487 as regards the adoption of the work programme for the gradual review of safeners and synergists
Commission Regulation (EU) 2025/2274 of 12 November 2025 amending Regulation (EU) 2024/1487 as regards the adoption of the work programme for the gradual review of safeners and synergists
Data as of 2026-07-04 · Compiled from an official source version. Later amendments or repeals may not be reflected; the official text prevails. · Read the official text ↗
Article 2
This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union .
Supplementary provisions
ANNEXSupplementary provisions
ANNEX Annex I to Regulation (EU) 2024/1487 is replaced by the following: ‘ANNEX I List of safeners and synergists included in the work programme for gradual review as referred to in Article 6(2) Safener Common name, ISO-name, and/or synonyms Chemical name (IUPAC and CA nomenclature) CAS number EC number Rapporteur Member State (RMS) Co-rapporteur Member State (Co-RMS) Cloquintocet mexyl Cloquintocet-mexyl heptan-2-yl 2-(5-chloroquinolin-8-yl)oxyacetate 99607-70-2 619-447-3 ES PT Cloquintocet Cloquintocet 2-[(5-chloroquinolin-8-yl)oxy]acetic acid 88349-88-6 635-476-4 and 926-839-0 ES PT Cyprosulfamide Cyprosulfamide N-[4-(cyclopropylcarbamoyl)phenyl]sulfonyl-2-methoxybenzamide 221667-31-8 619-679-5 NL BE Isoxadifen-ethyl Isoxadifen-ethyl ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate 163520-33-0 443-870-0 AT SI Mefenpyr-diethyl Mefenpyr-diethyl diethyl 1-(2,4-dichlorophenyl)-5-methyl-4H-pyrazole-3,5-dicarboxylate 135590-91-9 603-923-2 AT DE Metcamifen Metcamifen 2-methoxy-N-{4-[(methylcarbamoyl)amino]benzenesulfonyl}benzamide 129531-12-0 884-589-7 IT RO Synergist Common name, ISO-name, and/or synonyms Chemical name (IUPAC and CA nomenclature) CAS number EC number Rapporteur Member State (RMS) Co-rapporteur Member State (Co-RMS) Piperonyl butoxide Piperonyl butoxide 5-[2-(2-butoxyethoxy)ethoxymethyl]-6-propyl-1,3-benzodioxole 51-03-6 200-076-7 EL DE Rape seed oil Rape seed oil Not available 8002-13-9 Not available NL FI Edetic acid (EDTA) Edetic acid (EDTA) 2,2',2",2"'-(Ethane-1,2-diyldinitrilo)tetraacetic acid 60-00-4 200-449-4 DK PL Disodium EDTA dihydrate Disodium EDTA dihydrate disodium dihydrogen 2,2',2",2"'-(ethane-1,2- diyldinitrilo)tetraacetate dihydrate 6381-92-6 205-358-3 DK PL ’
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Source: EUR-Lex (Publications Office of the EU), © European Union, reuse permitted under Commission Decision 2011/833/EU.
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