Commission Implementing Regulation (EU) 2025/2505 of 11 December 2025 concerning the authorisation of guanidinoacetic acid and a preparation of guanidinoacetic acid as feed additives for weaned piglets and pigs for fattening in water for drinking and for turkeys for fattening and reared for breeding in feed and water for drinking (holder of authorisation: Alzchem Trostberg GmbH), and amending Implementing Regulation (EU) 2023/2628

Article 1Authorisation

The substance and the preparation specified in the Annex, belonging to the additive category ‘zootechnical additives’ and to the functional group ‘other zootechnical additives’, are authorised as additives in animal nutrition, subject to the conditions laid down in that Annex.

Article 2Amendment to Implementing Regulation (EU) 2023/2628

In Annex I to Implementing Regulation (EU) 2023/2628 in the column ‘Other provisions’ in each of the four tables the following point is added:
‘6.
Taking account of the actual intake of water for drinking relative to feed by the animals, it shall be ensured that the amount of guanidinoacetic acid administered via water for drinking is not higher than what it would be if fed at the maximum content of 1 200 mg/kg complete feed.’

Article 3Entry into force

This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union.

ANNEX

ANNEX
Identification number of the additive
Name of the holder of authorisation
Name of the additive
Composition, chemical formula, description, analytical method.
Species or category of animal
Maximum age
Minimum content
Maximum content
Other provisions
End of period of authorisation
mg guanidinoacetic acid/l of water for drinking
Category: Zootechnical additives. Functional group: other zootechnical additives (improvement of performance parameters)
4d372
Alzchem Trostberg GmbH
Guanidinoacetic acid
Additive composition
Guanidinoacetic acid 98 % on dry matter basis.
Solid form
Characterisation of the active substance
Guanidinoacetic acid produced by chemical synthesis
Chemical formula: C 3 H 7 N 3 O 2
CAS number: 352-97-6
Purity: 98 %
Impurities:
—
maximum cyanamide content 0,03 %;
—
maximum dicyandiamide content 0,5 %.
Analytical method
( 1 )
For the determination of guanidinoacetic acid in water for drinking: ion chromatography coupled with ultraviolet detection (IC-UV).
Weaned piglets
Pigs for fattening
-
200
600
1.
The moisture content shall be indicated on the labelling of the additive.
2.
The additive may be used via water for drinking.
3.
In the directions for use of the additive, the storage conditions and the stability in water for drinking shall be indicated.
4.
When using the additive, attention shall be paid to the supply with vitamin B 12 and methyl donors other than methionine in the diet of the animal.
5.
Simultaneous use of this additive in water for drinking and in feed is not permitted.
6.
Taking account of the actual intake of water for drinking relative to feed by the animals, it shall be ensured that the amount of guanidinoacetic acid administered via water for drinking is not lower than what it would be if fed at the minimum content of 600 mg/kg complete feed, nor higher than what it would be if fed at the maximum content of 1 200  mg/kg complete feed.
1 January 2036
Identification number of the additive
Name of the holder of authorisation
Name of the additive
Composition, chemical formula, description, analytical method.
Species or category of animal
Maximum age
Minimum content
Maximum content
Other provisions
End of period of authorisation
mg guanidinoacetic acid/l of water for drinking
Category: Zootechnical additives. Functional group: other zootechnical additives (improvement of performance parameters)
4d372i
Alzchem Trostberg GmbH
Guanidinoacetic acid
Additive composition
Preparation containing a minimum of 96 % of guanidinoacetic acid.
Solid form
Characterisation of the active substance
Guanidinoacetic acid produced by chemical synthesis
Chemical formula: C 3 H 7 N 3 O 2
CAS number: 352-97-6
Purity: 98 %
Impurities:
—
maximum cyanamide content 0,03 %;
—
maximum dicyandiamide content 0,5 %.
Analytical method
( 2 )
For the determination of guanidinoacetic acid in water for drinking: ion chromatography coupled with ultraviolet detection (IC-UV).
Weaned piglets
Pigs for fattening
-
200
600
1.
The moisture content shall be indicated on the labelling of the additive.
2.
The additive may be used via water for drinking.
3.
In the directions for use of the additive, the storage conditions and the stability in water for drinking shall be indicated.
4.
When using the additive, attention shall be paid to the supply with vitamin B 12 and methyl donors other than methionine in the diet of the animal.
5.
Simultaneous use of this additive in water for drinking and in feed is not permitted.
6.
Taking account of the actual intake of water for drinking relative to feed by the animals, it shall be ensured that the amount of guanidinoacetic acid administered via water for drinking is not lower than what it would be if fed at the minimum content of 600 mg/kg complete feed, nor higher than what it would be if fed at the maximum content of 1 200  mg/kg complete feed.
1 January 2036
Identification number of the additive
Name of the holder of authorisation
Name of the additive
Composition, chemical formula, description, analytical method.
Species or category of animal
Maximum age
Minimum content
Maximum content
Minimum content
Maximum content
Other provisions
End of period of authorisation
mg guanidinoacetic acid/kg of complete feed with a moisture content of 12 %
mg guanidinoacetic acid/l of water for drinking
Category: Zootechnical additives. Functional group: other zootechnical additives (improvement of performance parameters)
4d372
Alzchem Trostberg GmbH
Guanidinoacetic acid
Additive composition
Guanidinoacetic acid 98 % on a dry matter basis.
Solid form
Characterisation of the active substance
Guanidinoacetic acid produced by chemical synthesis
Chemical formula: C 3 H 7 N 3 O 2
CAS number: 352-97-6
Purity: 98 %
Impurities:
—
maximum cyanamide content 0,03 %;
—
maximum dicyandiamide content 0,5 %.
Analytical method
( 3 )
For the determination of guanidinoacetic acid in the feed additive, premixtures, compound feed and water for drinking: ion chromatography coupled with ultraviolet detection (IC-UV).
Turkeys for fattening
Turkeys reared for breeding
-
600
1 200
300
600
1.
The moisture content shall be indicated on the labelling of the additive.
2.
The additive may be used via water for drinking.
3.
In the directions for use of the additive and premixtures, the storage conditions, the stability to heat treatment and the stability in water for drinking shall be indicated.
4.
When using the additive, attention shall be paid to the supply with vitamin B 12 and methyl donors other than methionine in the diet of the animal.
5.
Simultaneous use of this additive in water for drinking and in feed is not permitted.
6.
Taking account of the actual intake of water for drinking relative to feed by the animals, it shall be ensured that the amount of guanidinoacetic acid administered via water for drinking is not higher than what it would be if fed at the maximum content of 1 200  mg/kg complete feed.
1 January 2036
Identification number of the additive
Name of the holder of authorisation
Name of the additive
Composition, chemical formula, description, analytical method.
Species or category of animal
Maximum age
Minimum content
Maximum content
Other provisions
End of period of authorisation
mg guanidinoacetic acid/kg of complete feed with a moisture content of 12 %
Category: Zootechnical additives. Functional group: other zootechnical additives (improvement of performance parameters)
4d372i
Alzchem Trostberg GmbH
Guanidinoacetic acid
Additive composition
Preparation containing a minimum of 96 % of guanidinoacetic acid.
Solid form
Characterisation of the active substance
Guanidinoacetic acid produced by chemical synthesis
Chemical formula: C 3 H 7 N 3 O 2
CAS number: 352-97-6
Purity: 98 %
Impurities:
—
maximum cyanamide content 0,03 %;
—
maximum dicyandiamide content 0,5 %.
Analytical method
( 4 )
For the determination of guanidinoacetic acid in the feed additive, premixtures and compound feed: ion chromatography coupled with ultraviolet detection (IC-UV).
Turkeys for fattening
Turkeys reared for breeding
-
600
1 200
1.
The moisture content shall be indicated on the labelling of the additive.
2.
In the directions for use of the additive and premixtures, the storage conditions and the stability to heat treatment shall be indicated.
3.
When using the additive, attention shall be paid to the supply with vitamin B 12 and methyl donors other than methionine in the diet of the animal.
1 January 2036
( 1 )   Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-evaluation-reports_en .
( 2 )   Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-evaluation-reports_en .
( 3 )   Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-evaluation-reports_en .
( 4 )   Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-evaluation-reports_en .

Schedules & Appendices

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