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Commission Regulation (EU) 2015/649 of 24 April 2015 amending Annex II to Regulation (EC) No 1333/2008 of the European Parliament and of the Council and the Annex to Commission Regulation (EU) No 231/2012 as regards the use of L-leucine as a carrier for table-top sweeteners in tablets (Text with EEA relevance)

Commission Regulation (EU) 2015/649 of 24 April 2015 amending Annex II to Regulation (EC) No 1333/2008 of the European Parliament and of the Council and the Annex to Commission Regulation (EU) No 231/2012 as regards the use of L-leucine as a carrier for table-top sweeteners in tablets (Text with EEA relevance)

Regulation (EU) 2015/649 · Regulation · 5 articles

Data as of 2026-07-04 · Compiled from an official source version. Later amendments or repeals may not be reflected; the official text prevails. · Read the official text ↗

Article 1

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Annex II to Regulation (EC) No 1333/2008 is amended in accordance with Annex I to this Regulation.

Article 2

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The Annex to Regulation (EU) No 231/2012 is amended in accordance with Annex II to this Regulation.

Article 3

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This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union .

Supplementary provisions

ANNEX ISupplementary provisions

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ANNEX I Annex II to Regulation (EC) No 1333/2008 is amended as follows: (1) In Part B, in Section 3 ‘Additives other than colours and sweeteners’, the following new entry is inserted after the entry for food additive E 640: ‘E 641 L-leucine’ (2) In part E, in food category 11.4.3 ‘Table-top sweeteners in tablets’, the following new entry is inserted after the entry for food additive E 640:   ‘E 641 L-leucine 50 000 ’

ANNEX IISupplementary provisions

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ANNEX II In the Annex to Regulation (EU) No 231/2012, the following new entry is inserted after the entry for E 640: ‘ E 641 L-LEUCINE Synonyms 2-Aminoisobutylacetic acid; L-2-Amino-4-methylvaleric acid; alpha-Aminoisocaproic acid; ( S )-2-Amino-4-methylpentanoic acid; L-Leu Definition Einecs 200-522-0 CAS number 61-90-5 Chemical name L-Leucine; L-2-Amino-4-methylpentanoic acid Chemical formula C 6 H 13 NO 2 Molecular Weight 131,17 Assay Content not less than 98,5 % and not more than 101,0 % on the anhydrous basis Description White or almost white crystalline powder or shiny flakes Identification Solubility Soluble in water, acetic acid, dilute HCl and alkaline hydroxides and carbonates; slightly soluble in ethanol Specific rotation [α] D 20 between + 14,5° and + 16,5° (4 % solution (anhydrous basis) in 6N HCl) Purity Loss on drying Not more than 0,5 % (100 °C – 105 °C) Sulphated Ash Not more than 0,1 % Chlorides Not more than 200 mg/kg Sulphates Not more than 300 mg/kg Ammonium Not more than 200 mg/kg Iron Not more than 10 mg/kg Arsenic Not more than 3 mg/kg Lead Not more than 5 mg/kg Mercury Not more than 1 mg/kg’

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Source: EUR-Lex (Publications Office of the EU), © European Union, reuse permitted under Commission Decision 2011/833/EU.

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