Commission Regulation (EU) 2021/383 of 3 March 2021 amending Annex III to Regulation (EC) No 1107/2009 of the European Parliament and of the Council listing co-formulants which are not accepted for inclusion in plant protection products (Text with EEA relevance)

Regulation (EU) 2021/383 · Regulation · 6 articles

Data as of 2026-07-04 · Compiled from an official source version. Later amendments or repeals may not be reflected; the official text prevails. · Read the official text ↗

Article 1

Annex III to Regulation (EC) No 1107/2009 is amended in accordance with the Annex to this Regulation.

Article 2

Member States which have granted authorisations for plant protection products containing co-formulants listed in Annex III to Regulation (EC) No 1107/2009, as amended by this Regulation, shall amend or withdraw those authorisations as soon as possible but no later than 24 March 2023.

Article 3

Member States shall not authorise the placing on the market or use of adjuvants containing co-formulants listed in Annex III to Regulation (EC) No 1107/2009, as amended by this Regulation. Member States which have authorised adjuvants containing co-formulants listed in Annex III to Regulation (EC) No 1107/2009, as amended by this Regulation, shall amend or withdraw those authorisations as soon as possible but no later than 24 March 2023.

Article 4

Any grace period granted by Member States in accordance with Article 46 of Regulation (EC) No 1107/2009 or national provisions for authorisation of adjuvants shall be as short as possible and shall expire for the sale and distribution at the latest 3 months and for the disposal, storage and use additional 9 months after the date of amendment or withdrawal of the authorisations referred to in Articles 2 and 3.

Article 5

This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union .

Supplementary provisions

ANNEXSupplementary provisions

ANNEX Annex III to Regulation (EC) No 1107/2009 is replaced by the following: ‘ANNEX III List of co-formulants which are not accepted for inclusion in plant protection products as referred to in Article 27 ( 1 ) No Name EC names/Other names CAS number EC number Classification/Other properties 1. 1-Chloro-2,3-epoxypropane Epichlorohydrin, 2,3-Epoxypropyl chloride 106-89-8 203-439-8 Carcinogenic cat.1B 2. 1,2- Dichloroethane 1,2-Dichloroethane; Ethane, 1,2-dichloro- 107-06-2 203-458-1 Carcinogenic cat.1B 3. 2-Ethoxyethanol 2-Ethoxyethanol; Ethanol, 2-ethoxy- 110-80-5 203-804-1 Toxic to reproduction cat.1B 4. 2-Ethoxyethyl acetate 2-Ethoxyethanol acetate; Ethanol, 2-ethoxy-, 1-acetate 111-15-9 203-839-2 Toxic to reproduction cat.1B 5. 1-Ethylpyrrolidin-2-one 1-Ethylpyrrolidin-2-one; N -ethyl-2-pyrrolidone 2687-91-4 220-250-6 Toxic to reproduction cat.1B 6. 2-Methoxyethanol 2-Methoxyethanol; Ethanol, 2-methoxy- 109-86-4 203-713-7 Toxic to reproduction cat.1B 7. 2-Methoxyethyl acetate 2-Methoxyethyl acetate; Ethanol, 2-methoxy-, 1-acetate; 2-Methoxyethanol acetate 110-49-6 203-772-9 Toxic to reproduction cat.1B 8. 2-Methoxypropanol 2-Methoxypropanol; 1-Propanol, 2-methoxy- 1589-47-5 216-455-5 Toxic to reproduction cat.1B 9. 1-Methylpyrrolidin-2-one 1-Methyl-2-pyrrolidone; 2-Pyrrolidinone, 1-methyl- 872-50-4 212-828-1 Toxic to reproduction cat.1B 10. 2-Nitropropane 2-Nitropropane; Propane, 2-nitro- 79-46-9 201-209-1 Carcinogenic cat.1B 11. Amines, tallow alkyl, ethoxylated Amines, tallow alkyl, ethoxylated; POE-tallowamine 61791-26-2 Concerns or data gaps related to potential effects on human health or the environment 12. Amines, tallow alkyl, ethoxylated propoxylated Amines, tallow alkyl, ethoxylated propoxylated; POEP-tallowamine 68213-26-3 Concerns or data gaps related to potential effects on human health or the environment 13. Asbestos fibres Actinolite asbestos; Asbestos, actinolyte 77536-66-4 Carcinogenic cat.1A 14. Amosite asbestos; Asbestos, amosite 12172-73-5 Carcinogenic cat.1A 15. Anthophyllite asbestos; Asbestos, anthophyllite 77536-67-5 Carcinogenic cat.1A 16. Chrysotile asbestos; Asbestol, chrysotile 12001-29-5 Carcinogenic cat.1A 17. Crocidolite asbestos; Asbestos, crocidolite 12001-28-4 Carcinogenic cat.1A 18. Tremolite asbestos; Asbestos, tremolite 77536-68-6 Carcinogenic cat.1A 19. Benzene Benzene 71-43-2 200-753-7 Carcinogenic cat.1A/ Mutagenic cat.1B 20. Benzo[def]chrysene; ( 2 ) Benzo[ pqr ]tetraphene Benzo[ def ]chrysene; Benzo[ a ]pyrene 50-32-8 200-028-5 Carcinogenic cat.1B/Mutagenic cat.1B/ Toxic to reproduction cat.1B 21. Bis(2-methylpropyl) benzene-1,2-dicarboxylate Diisobutyl phthalate 84-69-5 201-553-2 Endocrine disrupting properties (REACH Article 57(f) – Human Health) Toxic to reproduction cat.1B 22. Boric acid Boric acid 10043-35-3 11113-50-1 233-139-2 234-343-4 Toxic to reproduction cat.1B 23. Disodium octaborate Disodium octaborate; Disodium octaborate anhydrous 12008-41-2 234-541-0 Toxic to reproduction cat.1B 24. Disodium octaborate, tetrahydrate Boric acid, disodium salt, tetrahydrate; 12280-03-4 234-541-0 Toxic to reproduction cat.1B 25. Disodium tetraborate, anhydrous Disodium tetraborate, anhydrous; Boron sodium oxide 1330-43-4 215-540-4 Toxic to reproduction cat.1B 26. Disodium tetraborate, decahydrate Borax 1303-96-4 215-540-4 Toxic to reproduction cat.1B 27. Disodium tetraborate, pentahydrate Boron sodium oxide, hydrated 12179-04-3 215-540-4 Toxic to reproduction cat.1B 28. Orthoboric acid, sodium salt Orthoboric acid, sodium salt; Boric acid, sodium salt 13840-56-7 237-560-2 Toxic to reproduction cat.1B 29. Tetraboron disodium heptaoxide, hydrate Tetraboron disodium heptaoxide, hydrate; Boron sodium oxide, hydrate 12267-73-1 235-541-3 Toxic to reproduction cat.1B 30. Buta-1,3-diene Buta-1,3-diene; 1,3-Butadiene 106-99-0 203-450-8 Carcinogenic cat.1A/ Mutagenic cat.1B 31. Butane containing ≥ 0,1 % butadiene (EC No 203-450-8) Butane 106-97-8 203-448-7 Carcinogenic cat.1A 32. Co Poly (bisiminoimidocarbonyl, hexamethylene hydrochloride),(iminoimidocarbonyl, hexamethylene hydrochloride Guanidine, N , N" ’ -1,6-hexanediylbis[ N’ -cyano-, polymer with 1,6-hexanediamine, hydrochloride Poly[iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl], hydrochloride Cyanamide, N -cyano-, compd. with 1,6-hexanediamine (2:1), polymer with 1,6-hexanediamine hydrochloride (1:2); PHMB 27083-27-8 and 32289-58-0 and 1802181-67-4 Not approved for use in biocidal products for product-type 6 (in-can preservatives). 33. Dibutyl phthalate n -Butyl phthalate; Dibutyl benzene-1,2-dicarboxylate 84-74-2 201-557-4 Endocrine disrupting properties (REACH Article 57(f) – Human Health) Toxic to reproduction cat.1B 34. Distillates (petroleum), hydrotreated heavy naphthenic with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 64742-52-5 265-155-0 Carcinogenic cat.1B 35. Distillates (petroleum), hydrotreated heavy paraffinic with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 64742-54-7 265-157-1 Carcinogenic cat.1B 36. Distillates (petroleum), hydrotreated light naphthenic with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 64742-53-6 265-156-6 Carcinogenic cat.1B 37. Distillates (petroleum), hydrotreated light paraffinic with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 64742-55-8 265-158-7 Carcinogenic cat.1B 38. Distillates (petroleum), solvent-dewaxed heavy paraffinic with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 64742-65-0 265-169-7 Carcinogenic cat.1B 39. Distillates (petroleum), solvent-refined heavy paraffinic with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 64741-88-4 265-090-8 Carcinogenic cat.1B 40. Distillates (petroleum), solvent-refined light paraffinic with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 64741-89-5 265-091-3 Carcinogenic cat.1B 41. Ethylene oxide Ethylene oxide; Oxyrane; Epoxyethane 75-21-8 200-849-9 Carcinogenic cat.1B/ Mutagenic cat. 1B 42. Formaldehyde Formaldehyde; Formalin; Methanal;,Formol 50-00-0 200-001-8 Carcinogenic cat.1B 43. Formamide Formamide; Methanamide 75-12-7 200-842-0 Toxic to reproduction cat.1B 44. Isobutane (containing ≥ 0,1 % butadiene (EC No 203-450-8)) Isobutane; Propane, 2-methyl- 75-28-5 200-857-2 Carcinogenic cat.1A/ Mutagenic cat. 1B 45. Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based, high-viscosity with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 72623-85-9 276-736-3 Carcinogenic cat.1B 46. Lubricating oils (petroleum), C15-30, hydrotreated neutral oil-based with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 72623-86-0 276-737-9 Carcinogenic cat.1B 47. Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 72623-87-1 276-738-4 Carcinogenic cat.1B 48. Lubricating oils (petroleum), C17-32, solvent-extd., dewaxed, hydrogenated with a content of ≥ 3,0 % DMSO-extract (measured by IP 346) 101316-70-5 309-875-6 Carcinogenic cat.1B 49. Naphtha (petroleum), heavy alkylate predominantly branched chain C9-C12 with a content of ≥ 0,1 % benzene (EC No 200-753-7) 64741-65-7 265-067-2 Carcinogenic cat.1B/ Mutagenic cat.1B 50. Naphtha (petroleum), hydrodesulfurized heavy predominantly C7-C12 with a content of ≥ 0,1 % benzene (EC No 200-753-7) 64742-82-1 265-185-4 Carcinogenic cat.1A/ Mutagenic cat.1B 51. Naphtha (petroleum), hydrodesulfurized light, dearomatized predominantly C7 paraffins and cycloparaffins with a content of ≥ 0,1 % benzene (EC No 200-753-7) 92045-53-9 295-434-2 Carcinogenic cat.1A/ Mutagenic cat.1B 52. Naphtha (petroleum), hydrotreated heavy predominantly C6-C13 with a content of ≥ 0,1 % benzene (EC No 200-753-7) 64742-48-9 265-150-3 Carcinogenic cat.1A/ Mutagenic cat.1B 53. Naphtha (petroleum), light aromatic predominantly C8-C10 with a content of ≥ 0,1 % benzene (EC N. 200-753-7) 64742-95-6 265-199-0 Carcinogenic cat.1A/ Mutagenic cat.1B 54. Nitrobenzene Nitrobenzene; Benzene, nitro- 98-95-3 202-716-0 Toxic to reproduction cat.1B 55. N -methylformamide N -methylformamide; Formamide, N -methyl- 123-39-7 204-624-6 Toxic to reproduction cat.1B 56. Nonyl-phenols: Substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in any position to phenol, covering also substances which include any of the individual isomers or a combination thereof. 4-(3,5-Dimethylheptan-3-yl)phenol Phenol, 4-(1-ethyl-1,3-dimethylpentyl)-; 4-(1-Ethyl-1,3-dimethylpentyl)phenol 186825-36-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 57. 4-(3,6-Dimethylheptan-3-yl)phenol Phenol, 4-(1-ethyl-1,4-dimethylpentyl)-; 4-(1-Ethyl-1,4-dimethylpentyl)phenol 142731-63-3 Endocrine disrupting properties (REACH Article 57(f) – Environment) 58. 4-(2-Methyloctan-2-yl)phenol p- (1,1-Dimethylheptyl)phenol; Phenol, 4-(1,1-dimethylheptyl)- 30784-30-6 250-339-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 59. 4-(3-Methyloctan-3-yl)phenol Phenol, 4-(1-ethyl-1-methylhexyl)-; 4-(1-Ethyl-1-methylhexyl)phenol; 52427-13-1 257-907-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 60. 4-Nonylphenol p- Nonylphenol; Phenol, 4-nonyl- 104-40-5 203-199-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 61. Isononylphenol 11066-49-2 234-284-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 62. p -Isononylphenol; Phenol, 4-isononyl- 26543-97-5 247-770-6 Endocrine disrupting properties (REACH Article 57(f) – Environment) 63. Nonylphenol; Phenol, nonyl- 25154-52-3 246-672-0 Endocrine disrupting properties (REACH Article 57(f) – Environment) 64. Phenol, 4-(1-methyloctyl)-; p- (1-Methyloctyl)phenol 17404-66-9 241-427-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 65. Phenol, 4-nonyl-, branched 84852-15-3 284-325-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 66. Phenol, nonyl-, branched 90481-04-2 291-844-0 Endocrine disrupting properties (REACH Article 57(f) – Environment) 67. Nonyl-phenols, ethoxylated: Substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in any position to phenol, ethoxylated, covering also substances which include any of the individual isomers or a combination thereof. Nonylphenol, ethoxylated; Poly(oxy-1,2-ethanediyl), α-(nonylphenyl)-ω-hydroxy- 500-024-6 Endocrine disrupting properties (REACH Article 57(f) – Environment) 68. 4-Nonylphenol, branched, 1 – 2,5 moles ethoxylated Poly(oxy-1,2-ethanediyl), α-(4-nonylphenyl)-ω-hydroxy-, branched 500-315-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 69. 4-Nonylphenol, 1 – 2,5 moles ethoxylated 500-045-0 Endocrine disrupting properties (REACH Article 57(f) – Environment) 70. 2-(2-{2-[2-(4-Nonylphenoxy)ethoxy]ethoxy}ethoxy)ethan-1-ol 2-[2-[2-[2-(4-Nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol; Ethanol, 2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]- 7311-27-5 230-770-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 71. 2-[2-(4-Nonylphenoxy)ethoxy]ethanol; Ethanol, 2-[2-(4-nonylphenoxy)ethoxy]- 20427-84-3 243-816-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 72. 20-(4-Nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol; 3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20- (4-nonylphenoxy)- 27942-27-4 248-743-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 73. 2-[2-[2-[2-(4-Nonylphenoxy)ethoxy]ethoxy]ethoxy]ethan-1-ol Ethanol,2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]- 7311-27-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 74. 26-(4-Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-(4-nonylphenoxy)- 14409-72-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 75. 17-(4-Nonylphenoxy)-3,6,9,12,15-pentaoxaheptadecan-1-ol 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-(4-nonylphenoxy)- 34166-38-6 Endocrine disrupting properties (REACH Article 57(f) – Environment) 76. Poly(oxy-1,2-ethanediyl), α-(4-nonylphenyl)-ω-hydroxy-, branched 127087-87-0 Endocrine disrupting properties (REACH Article 57(f) – Environment) 77. Poly(oxy-1,2-ethanediyl), α-(4-nonylphenyl)-ω-hydroxy- 26027-38-3 Endocrine disrupting properties (REACH Article 57(f) – Environment) 78. Ethanol, 2-(4-nonylphenoxy) 104-35-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 79. Isononylphenol, ethoxylated; Poly(oxy-1,2-ethanediyl), α-(isononylphenyl)-ω-hydroxy- 37205-87-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 80. 2-[2-(4- tert -Nonylphenoxy) ethoxy] ethanol Ethanol, 2-[2-(4- tert -nonylphenoxy)ethoxy]- 156609-10-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 81. Poly(oxy-1,2-ethanediyl), α-(nonylphenyl)-ω-hydroxy- Nonylphenol, ethoxylated 9016-45-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 82. Octyl-phenols: Substances with a linear and/or branched alkyl chain with a carbon number of 8 covalently bound in any position to phenol, covering also substances which include any of the individual isomers or a combination thereof. p- Octylphenol; 4-Octylphenol 1806-26-4 217-302-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 83. 4-(2,4,4-Trimethylpentan-2-yl)phenol; 4-(1,1,3,3-Tetramethylbutyl)phenol; 4-( tert -octyl) Phenol Phenol, 4-(1,1,3,3-tetramethylbutyl)-; 4- tert -Octylphenol 140-66-9 205-426-2 Endocrine disrupting properties (REACH Article 57(f) – Environment) 84. Octylphenol; Phenol, octyl- 67554-50-1 266-717-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 85. Phenol, 2-isooctyl- 86378-08-7 Endocrine disrupting properties (REACH Article 57(f) – Environment) 86. Phenol, isooctyl-; Isooctylphenol 11081-15-5 234-304-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 87. Phenol, 2-octyl-; o -Octylphenol 949-13-3 213-437-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 88. Phenol, 2- sec- octyl-; o - sec- Octylphenol 26401-75-2 247-663-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 89. Phenol, 4-isooctyl-; p -Isooctylphenol 27013-89-4 248-164-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 90. Phenol, 4- sec- octyl-; p - sec -Octylphenol 27214-47-7 248-330-6 Endocrine disrupting properties (REACH Article 57(f) – Environment) 91. Phenol, sec- octyl-; sec -Octylphenol 93891-78-2 299-461-0 Endocrine disrupting properties (REACH Article 57(f) – Environment) 92. Phenol, 4-(1-ethylhexyl)-; p -(1-Ethylhexyl)phenol 3307-00-4 221-989-7 Endocrine disrupting properties (REACH Article 57(f) – Environment) 93. Phenol, 2-(1-methylheptyl)-; o -(1Methylheptyl)phenol 18626-98-7 242-459-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 94. Phenol, 2-(1-ethylhexyl)-; o -(1-Ethylhexyl)phenol 17404-44-3 241-426-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 95. Phenol, 2-(1-propylpentyl)-; o -(1-Propylpentyl)phenol 37631-10-0 253-574-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 96. Phenol, 4-(1-propylpentyl)-; p -(1-Propylpentyl)phenol 3307 - 01-5 221-990-2 Endocrine disrupting properties (REACH Article 57(f) – Environment) 97. Phenol, 2-(1-methylheptyl)-; o -(1,1,3,3-Tetramethylbutyl)phenol 3884-95-5 223-420-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 98. Phenol, (1,1,3,3-tetramethylbutyl)-; (1,1,3,3-Tetramethylbutyl)phenol 27193-28-8 248-310-7 Endocrine disrupting properties (REACH Article 57(f) – Environment) 99. Phenol, (1-methylheptyl)-; (1-Methylheptyl)phenol 27985-70-2 248-759-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 100. Phenol, 4-(2-methylheptyl)- 898546-19-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 101. Phenol, 2-(2-ethylhexyl)- 28752-62-7 Endocrine disrupting properties (REACH Article 57(f) – Environment) 102. Phenol, 4-(1-methylheptyl)-; p- (1-Methylheptyl)phenol 1818-08-2 217-332-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 103. Phenol, 4-(2-ethylhexyl)- 69468-20-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 104. Phenol, 4-(5-methylheptyl)- 1824164-95-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 105. Phenol, 2-(2-methylheptyl)- 898546-20-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 106. Phenol, 4-(2-propylpentyl)- 119747-99-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 107. Phenol, 3-octyl- 20056-69-3 Endocrine disrupting properties (REACH Article 57(f) – Environment) 108. Phenol, 2-(1,1-dimethylhexyl)- 1824575-79-2 Endocrine disrupting properties (REACH Article 57(f) – Environment) 109. Phenol, 4-(1,1-dimethylhexyl)- 30784-29-3 Endocrine disrupting properties (REACH Article 57(f) – Environment) 110. Phenol, 4-(5,5-dimethylhexyl)- 13330-52-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 111. Phenol, 2-(5,5-dimethylhexyl)- 1822989-97-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 112. Phenol, 3-(1,1-dimethylhexyl)- 70435-92-6 Endocrine disrupting properties (REACH Article 57(f) – Environment) 113. Phenol, 4-(1,4-dimethylhexyl)- 164219-26-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 114. Octyl-phenols, ethoxylated: Substances with a linear and/or branched alkyl chain with a carbon number of 8 covalently bound in any position to phenol, ethoxylated, covering also substances which include any of the individual isomers or a combination thereof. Poly(oxy-1,2-ethanediyl), α-[(1,1,3,3- tetramethylbutyl) phenyl]-ω-hydroxy- 2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol Polyethylene Glycol Octylphenyl Ether; 9036-19-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 115. 2-[4-(2,4,4-Trimethylpentan-2-yl)phenoxy]ethanol Poly(oxy-1,2-ethanediyl), α-[4-(1,1,3,3-tetramethylbutyl)phenyl]-ω-hydroxy- Octylphenol ethoxylated 9002-93-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 116. 20-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-ol 3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-[4-(1,1,3,3-tetramethylbutyl)phenoxy]- 2497-59-8 219-682-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 117. Ethanol, 2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]- 2315-67-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 118. Ethanol, 2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]- 2315-61-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 119. 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-(4-octylphenoxy)-; 42173-90-0 255-695-5 Endocrine disrupting properties (REACH Article 57(f) – Environment) 120. Poly(oxy-1,2-ethanediyl), α-(octylphenyl)-ω-hydroxy-, branched 68987-90-6 Endocrine disrupting properties (REACH Article 57(f) – Environment) 121. Poly(oxy-1,2-ethanediyl), α-[4-(6-methylheptyl)phenyl]-ω-hydroxy- 59379-12-3 Endocrine disrupting properties (REACH Article 57(f) – Environment) 122. Ethanol, 2-(4-octylphenoxy)-; 2-( p- Octylphenoxy)ethanol 51437-89-9 257-203-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 123. Poly(oxy-1,2-ethanediyl), α-(4-octylphenyl)-ω-hydroxy- 26636-32-8 Endocrine disrupting properties (REACH Article 57(f) – Environment) 124. Poly(oxy-1,2-ethanediyl), α-[4-(1-methylheptyl)phenyl]-ω-hydroxy- 73935-42-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 125. 3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-(4-octylphenoxy)-; 20-(4-Octylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol 32742-88-4 251-190-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 126. Ethanol, 2-[2-[2-[2-(4-octylphenoxy)ethoxy]ethoxy]ethoxy]-; 2-( p- Octylphenoxy)ethanol 51437-92-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 127. Ethanol, 2-[2-(4-octylphenoxy)ethoxy]- 51437-90-2 Endocrine disrupting properties (REACH Article 57(f) – Environment) 128. 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-(4-octylphenoxy)- 51437-94-6 Endocrine disrupting properties (REACH Article 57(f) – Environment) 129. Poly(oxy-1,2-ethanediyl), α-(isooctylphenyl)-ω-hydroxy- 9004-87-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 130. 2-[2-[2-(4-Octylphenoxy)ethoxy]ethoxy]ethanol 51437-91-3 Endocrine disrupting properties (REACH Article 57(f) – Environment) 131. 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-[4-(1,1,3,3-tetramethylbutyl)phenoxy]- 2497-58-7 Endocrine disrupting properties (REACH Article 57(f) – Environment) 132. Ethanol, 2-[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethoxy]- 2315-62-0 Endocrine disrupting properties (REACH Article 57(f) – Environment) 133. Ethanol, 2-[2-[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethoxy]ethoxy]- 2315-63-1 Endocrine disrupting properties (REACH Article 57(f) – Environment) 134. 3,6,9,12-Tetraoxatetradecan-1-ol, 14-[4-(1,1,3,3-tetramethylbutyl)phenoxy]- 2315-64-2 Endocrine disrupting properties (REACH Article 57(f) – Environment) 135. 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-[4-(1,1,3,3-tetramethylbutyl)phenoxy]- 2315-65-3 Endocrine disrupting properties (REACH Article 57(f) – Environment) 136. 3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-[4-(1,1,3,3-tetramethylbutyl)phenoxy]- 2315-66-4 Endocrine disrupting properties (REACH Article 57(f) – Environment) 137. Ethanol, 2-[3-(1,1,3,3-tetramethylbutyl)phenoxy]- 1026254-24-9 Endocrine disrupting properties (REACH Article 57(f) – Environment) 138. Ethanol, 2-[2-(1,1,3,3-tetramethylbutyl)phenoxy]- 84658-53-7 Endocrine disrupting properties (REACH Article 57(f) – Environment) 139. Ethanol, 2-[2-(octylphenoxy)ethoxy]- 27176-92-7 Endocrine disrupting properties (REACH Article 57(f) – Environment) 140. N , N -Dimethylformamide N , N -dimethylformamide; Dimethyl formamide, DMF 68-12-2 200-679-5 Toxic to reproduction cat.1B 141. Prop-2-enamide Acrylamide; 2-propenamide 79-06-1 201-173-7 Carcinogenic cat.1B/ Mutagenic cat.1B 142. Pyridine, alkyl derivatives, with a content of ≥ 0,1 % benzene (EC No 200-753-7) 68391-11-7 269-929-9 Carcinogenic cat.1A/ Mutagenic cat.1B 143. Quinoline Quinoline 91-22-5 202-051-6 Carcinogenic cat.1B 144. Tetrahydrofurfuryl Alcohol Tetrahydrofurfuryl alcohol; 2-Furanmethanol, tetrahydro- 97-99-4 202-625-6 Toxic to reproduction cat.1B ’ ( 1 ) The limit for the acceptable presence of the substances listed in the table as unintentional impurity in the finished product is 0,1 % (weight by weight (w/w)) except where stated otherwise in this Annex. ( 2 ) The limit for the acceptable presence of this substance as unintentional impurity in the finished product is 0,01 % (weight by weight (w/w)), corresponding to the specific concentration limit set in Annex VI to Regulation (EC) No 1272/2008.

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